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Structure of 374068-01-6
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2-Chloropyrimidine-5-carboxylic acid features a chlorine-substituted pyrimidine core paired with a carboxylic acid group, enabling direct functionalization in heterocyclic synthesis. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and bioactive molecule frameworks under standard conditions.
2-Chloropyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C5 position via nucleophilic substitution. Its carboxylic acid group facilitates amide coupling and esterification, while the chloro substituent offers reliable electrophilic reactivity under mild conditions. The scaffold exhibits excellent bench stability and compatibility with standard purification techniques, making it well-suited for modular synthesis of heterocyclic compounds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: