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CS-W001157 4
Total: USD 88.00

4-Iodo-2-hydroxybenzaldehyde

  • CAS No. 38170-02-4

  • Cat. No. CS-0040703
  • Purity≥98%
  • MDL No.MFCD08457196
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Iodo-2-hydroxybenzaldehyde|CS-0040703

Structure of 38170-02-4

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Description

4-Iodo-2-hydroxybenzaldehyde features a strategically positioned aldehyde group flanked by iodine and phenolic hydroxyl moieties, enabling direct functionalization in cross-coupling and derivatization workflows. The ortho-hydroxyl enhances chelation potential and modulates electronic properties, while the iodo substituent provides a high-reactivity handle for palladium-catalyzed transformations under standard conditions.

Application

4-Iodo-2-hydroxybenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its iodine substituent. The ortho-hydroxyl and aldehyde groups provide orthogonal functionality for sequential transformations, including derivatization via condensation or protection strategies. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for the construction of complex heterocyclic scaffolds and functionalized aromatic intermediates in medicinal chemistry workflows.

General Information

  • CAS No. 38170-02-4
  • Cat. No. CS-0040703
  • Purity ≥98%
  • MDL No. MFCD08457196
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅IO₂
  • Molecular Weight 248.02
  • Synonym(s) 2-Hydroxy-4-iodobenzaldehyde
  • SMILES O=CC1=CC=C(I)C=C1O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.8093
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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