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Structure of 626-02-8
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m-Iodophenol features a para-iodinated aromatic ring with a hydroxyl group positioned ortho to the iodine, enabling selective functionalization in cross-coupling reactions. This configuration enhances reactivity while maintaining stability under standard conditions, making it ideal for synthesizing iodinated arenes and advanced pharmaceutical intermediates.
m-Iodophenol serves as a versatile aryl iodide building block in cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation under palladium-catalyzed conditions. Its ortho-iodo substitution provides enhanced reactivity in Suzuki-Miyaura, Stille, and Negishi couplings, while the phenolic hydroxyl group offers complementary functionality for derivatization or protection. The compound exhibits good bench stability and facilitates straightforward purification, making it a practical choice for synthetic sequences in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: