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Structure of 381722-48-1
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tert-Butyl 4-(piperazin-1-ylmethyl)piperidine-1-carboxylate features a piperazine-modified piperidine scaffold with a tert-butoxycarbonyl protecting group, enabling straightforward deprotection and functionalization. The pendant piperazinylmethyl moiety offers enhanced solubility and hydrogen-bonding capacity, facilitating integration into bioactive molecules. This compound serves as a key intermediate in the synthesis of CNS-targeted therapeutics and kinase inhibitors.
tert-Butyl 4-(piperazin-1-ylmethyl)piperidine-1-carboxylate serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient access to complex nitrogen-rich scaffolds. The piperazinylmethyl group provides a flexible linker with enhanced solubility and hydrogen-bonding capacity, while the tert-butyl carbamate offers stable protection under standard conditions. It facilitates rapid diversification via orthogonal deprotection and coupling strategies, supporting late-stage functionalization in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: