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CS-W001157 4
Total: USD 88.00

2,6-Di-tert-butyl-4-methylpyridine

  • CAS No. 38222-83-2

  • Cat. No. CS-W007500
  • Purity≥98%
  • MDL No.MFCD00006305

*For research and further manufacturing use only, not for direct human use.

2,6-Di-tert-butyl-4-methylpyridine|CS-W007500

Structure of 38222-83-2

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General Information

  • CAS No. 38222-83-2
  • Cat. No. CS-W007500
  • Purity ≥98%
  • MDL No. MFCD00006305
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₃N
  • Molecular Weight 205.34
  • Synonym(s) None
  • SMILES CC1=CC(C(C)(C)C)=NC(C(C)(C)C)=C1

Description

2,6-Di-tert-butyl-4-methylpyridine is a sterically hindered, non-nucleophilic base which distinguishes between Brnsted (protonic) and Lewis acids. It also enables the direct high-yield conversion of aldehydes and ketones to vinyl triflates. It inhibits desilylation and hydration of the products during GaCl3-catalyzed ortho-ethynylation of phenol.2,6-Di-tert-butyl-4-methylpyridine has been used:in the synthesis of 1,2-dihydro-2-silanaphthalene derivativesas base in PtCl4-catalyzed cyclization reactions of homopropargyl azide derivativesdiastereoselective synthesis of -thiomannopyranosides

Synthesis

  • Route1
    • In-stock
      Trimethylacetonitrile|CS-0017904
      630-18-2
    • null|null
      41792-83-0
    • ~30%
    • In-stock
      2,6-Di-tert-butyl-4-methylpyridine|CS-W007500
      38222-83-2

    References

    • Bates, Robert B.; Gordon, Bernard; Keller, Philip C.; Rund, John V.; Mills, Nancy S., Journal of Organic Chemistry, 1980 , vol. 45, # 1 p. 168 - 169
  • Route2
    • null|null
      3282-30-2
    • ~%
    • In-stock
      2,6-Di-tert-butyl-4-methylpyridine|CS-W007500
      38222-83-2

    References

    • Balaban; Nenitzescu Justus Liebigs Annalen der Chemie, 1959 , vol. 625, p. 74,83
  • Route3
    • null|null
      75-85-4
    • null|null
      1538-75-6
    • ~%
    • In-stock
      2,6-Di-tert-butyl-4-methylpyridine|CS-W007500
      38222-83-2
    • null|null
      108154-12-7
    • null|null
      108154-13-8

    References

    • Rajoharison, Harivelo G.; Roussel, Christian Bulletin de la Societe Chimique de France, 1986 , # 2 p. 307 - 313

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.98502
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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