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Structure of 630-18-2
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Trimethylacetonitrile offers a sterically hindered nitrile functionality ideal for nucleophilic substitution reactions. This bench-stable, moisture-tolerant solvent features enhanced solubility for polar intermediates and facilitates clean reaction profiles under standard conditions.
Trimethylacetonitrile serves as a polar aprotic solvent with enhanced stability and low nucleophilicity, enabling efficient reactions in organometallic synthesis and transition-metal-catalyzed transformations. Its branched alkyl structure imparts excellent bench stability, minimal side reactivity, and facilitates straightforward purification, making it well-suited for sensitive coupling protocols and scale-up applications in pharmaceutical and fine chemical R&D.
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GHS Pictogram :
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GHS No : GHS02,GHS06
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Signal Word : Danger
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UN#: 1992
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Class : 3(6.1)
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Packing Group : Ⅱ
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Hazard Statements : H225-H301+H311+H331
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: