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Structure of 383907-17-3
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3-Amino-2-methyl-6-(trifluoromethyl)pyridine features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the amino substituent provides a reactive handle for derivatization. This scaffold integrates readily into pharmaceutical intermediates and functional materials, offering improved solubility and thermal resilience under standard conditions.
3-Amino-2-methyl-6-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles via standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the amino and methyl substituents provide orthogonal handles for further derivatization. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis campaigns and API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: