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Structure of 38674-21-4
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1-Oxa-7-azaspiro[3.5]nonane features a rigid spirocyclic architecture integrating an oxygen atom and a nitrogen heteroatom within a fused 3,5-ring system. This configuration imparts enhanced stability and distinct polarity, enabling its use as a privileged scaffold in medicinal chemistry for probing bioactive conformational space.
1-Oxa-7-azaspiro[3.5]nonane serves as a rigid, conformationally constrained heterocyclic scaffold with demonstrated utility in medicinal chemistry lead optimization. Its spirocyclic architecture combines an oxygen and nitrogen atom within a fused 7-membered ring system, enabling precise spatial positioning of substituents. The compound exhibits excellent bench stability, tolerates a range of functional groups, and participates reliably in standard coupling reactions, facilitating the construction of complex molecular architectures relevant to API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: