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(9H-Fluoren-9-yl)methyl4-(aminomethyl)piperidine-1-carboxylatehydrochloride

  • CAS No. 391248-14-9

  • Cat. No. CS-0171446
  • Purity≥96%
  • MDL No.MFCD02179398

*For research and further manufacturing use only, not for direct human use.

(9H-Fluoren-9-yl)methyl4-(aminomethyl)piperidine-1-carboxylatehydrochloride|CS-0171446

Structure of 391248-14-9

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General Information

  • CAS No. 391248-14-9
  • Cat. No. CS-0171446
  • Purity ≥96%
  • MDL No. MFCD02179398
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₅ClN₂O₂
  • Molecular Weight 372.89
  • Synonym(s) 9H-fluoren-9-ylmethyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride
  • SMILES C1=CC=C2C(=C1)C3=CC=CC=C3C2COC(=O)N4CCC(CC4)CN.Cl

Description

This fluorenylmethyl-protected piperidine derivative delivers a robust, bench-stable scaffold for peptide synthesis and bioconjugation. The protected amine enables efficient coupling under standard conditions, while the piperidine ring provides enhanced solubility and structural flexibility in complex molecular architectures.

Application

(9H-Fluoren-9-yl)methyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride serves as a robust, bench-stable building block for peptide and medicinal chemistry applications. The fluorenylmethoxycarbonyl (Fmoc) group enables efficient N-terminal protection in solid-phase synthesis, while the piperidine-based side chain provides a versatile amine handle for conjugation or derivatization. Its hydrochloride salt form enhances solubility and handling, facilitating purification and integration into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H410
Precautionary Statements : P273-P391-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   4.028
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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