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CS-W001157 4
Total: USD 88.00

4,5-Dichloro-1H-pyrrole-2-carboxylic acid

  • CAS No. 39209-94-4

  • Cat. No. CS-0060159
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4,5-Dichloro-1H-pyrrole-2-carboxylic acid|CS-0060159

Structure of 39209-94-4

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Description

4,5-Dichloro-1H-pyrrole-2-carboxylic acid features a highly electron-deficient pyrrole core flanked by two chlorine substituents, enhancing reactivity in cross-coupling and cyclization processes. The carboxylic acid group enables direct derivatization or metal complexation, offering utility in medicinal chemistry scaffolds and functional materials synthesis under standard conditions.

Application

4,5-Dichloro-1H-pyrrole-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the C2 position via standard carboxylic acid transformations. The electron-deficient pyrrole core exhibits enhanced stability and predictable reactivity in coupling reactions, facilitating access to substituted pyrroles used in medicinal chemistry and agrochemical scaffolds. Its bench-stable nature and compatibility with common purification methods support reliable integration into multi-step syntheses.

General Information

  • CAS No. 39209-94-4
  • Cat. No. CS-0060159
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃Cl₂NO₂
  • Molecular Weight 179.99
  • Synonym(s) 4,5-dichloropyrrole-2-carboxylic acid
  • SMILES C1=C(C(=O)O)NC(=C1Cl)Cl

Computational Chemistry Data

  • TPSA   53.09
  • LogP   2.0197
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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