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CS-W001157 4
Total: USD 88.00

2-(Hydroxymethyl)-4-nitrophenol

  • CAS No. 39224-61-8

  • Cat. No. CS-0099779
  • Purity≥98%
  • MDL No.MFCD01321361

*For research and further manufacturing use only, not for direct human use.

2-(Hydroxymethyl)-4-nitrophenol|CS-0099779

Structure of 39224-61-8

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General Information

  • CAS No. 39224-61-8
  • Cat. No. CS-0099779
  • Purity ≥98%
  • MDL No. MFCD01321361
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₄
  • Molecular Weight None
  • Synonym(s) 5-Nitrosalicyl Alcohol
  • SMILES OCC1=CC([N+]([O-])=O)=CC=C1O

Description

2-(Hydroxymethyl)-4-nitrophenol features a phenolic hydroxyl group paired with a para-nitro substituent, delivering strong electron-withdrawing character and enhanced solubility in polar solvents. The hydroxymethyl functionality enables direct derivatization for conjugation or polymer integration, making it valuable in synthetic intermediates and functional material design.

Synthesis

  • Route1

    References

    • Hangauer, David G. Patent: US2008/4241 A1, 2008 ; Location in patent: Page/Page column 75 ; US 20080004241 A1
  • Route2
    • 2-Hydroxy-5-nitrobenzoic acid Mesalazine  Impurity|CS-0229167
      96-97-9
    • ~90%
    • In-stock
      2-(Hydroxymethyl)-4-nitrophenol|CS-0099779
      39224-61-8

    References

    • Zhou, Yuhan; Gao, Guchao; Li, Hui; Qu, Jingping Tetrahedron Letters, 2008 , vol. 49, # 20 p. 3260 - 3263
  • Route3
    • null|null
      1030832-68-8
    • ~28%
    • In-stock
      2-(Hydroxymethyl)-4-nitrophenol|CS-0099779
      39224-61-8
    • 5-Nitrobenzo[c][1,2]oxaborol-1(3H)-ol|CS-0972755
      875816-94-7
    • null|null
      1447933-59-6

    References

    • Cao, Sheng; Christiansen, Robin; Peng, Xiaohua Chemistry - A European Journal, 2013 , vol. 19, # 27 p. 9050 - 9058

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   83.6
  • LogP   0.7927
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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