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CS-W001157 4
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(R)-tert-Butyl methyl(pyrrolidin-3-yl)carbamate

  • CAS No. 392338-15-7

  • Cat. No. CS-W003610
  • Purity≥95%
  • MDL No.MFCD09263387
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

(R)-tert-Butyl methyl(pyrrolidin-3-yl)carbamate|CS-W003610

Structure of 392338-15-7

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Description

(R)-tert-Butyl methyl(pyrrolidin-3-yl)carbamate is a chiral building block featuring a stereodefined pyrrolidin-3-yl moiety and a bench-stable carbamate handle. This configuration enables selective coupling in asymmetric synthesis, particularly in the construction of nitrogen-containing heterocycles and bioactive scaffolds. The tert-butyl group provides protection under standard conditions, while the methyl substitution enhances solubility and modulates reactivity.

Application

(R)-tert-Butyl methyl(pyrrolidin-3-yl)carbamate serves as a stereochemically defined, bench-stable building block for the synthesis of bioactive nitrogen-containing scaffolds. Its pyrrolidin-3-ylcarbamate moiety enables direct incorporation into peptidomimetics and heterocyclic drug candidates via standard coupling and cyclization protocols. The tert-butyl and methyl groups provide orthogonal protection, facilitating selective deprotection during multi-step synthesis. Functions reliably in diverse reaction environments with high functional group tolerance.

General Information

  • CAS No. 392338-15-7
  • Cat. No. CS-W003610
  • Purity ≥95%
  • MDL No. MFCD09263387
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂O₂
  • Molecular Weight 200.28
  • Synonym(s) METHYL-PYRROLIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER
  • SMILES O=C(N([C@H]1CNCC1)C)OC(C)(C)C

Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.2152
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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