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Structure of 393-06-6
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4-Amino-2-(trifluoromethyl)benzoic acid features a strategically positioned trifluoromethyl group enhancing electron-withdrawal and metabolic stability, while the para-amino substituent provides a reactive handle for conjugation. This dual-functional architecture enables integration into bioconjugates, pharmaceutical intermediates, and functional materials under standard conditions.
4-Amino-2-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its amino and carboxylic acid functionalities offer orthogonal reactivity for peptide coupling, amidation, and electrophilic substitution. The electron-withdrawing trifluoromethyl group enhances metabolic stability and modulates electronic properties, while the compound exhibits good bench stability and ease of purification in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: