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Structure of 39478-78-9
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5-Bromo-2-methylaniline features a bromine substituent at the 5-position and a methyl group at the 2-position relative to the amino functionality, creating a sterically hindered, electron-rich aromatic system. This configuration enhances stability under standard bench conditions while enabling selective coupling reactions in pharmaceutical synthesis and dye development.
5-Bromo-2-methylaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the aniline nitrogen and ortho-position. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: