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Structure of 399-95-1
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3-Fluoro-4-aminophenol features a fluorine atom at the meta position relative to an electron-rich amino group, creating a unique electronic profile ideal for targeted conjugation. This bench-stable phenolic scaffold integrates seamlessly into bioconjugates and pharmaceutical intermediates, where regioselective reactivity enhances synthetic efficiency in complex molecule assembly.
3-Fluoro-4-aminophenol serves as a key building block in the synthesis of fluorinated aromatic amines and heterocyclic scaffolds. Its dual functionality enables direct coupling reactions, including Suzuki-Miyaura and Ullmann-type transformations, while maintaining bench stability and ease of purification. The ortho-fluoro and para-amino groups offer complementary reactivity for sequential functionalization, making it a valuable intermediate in medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07,GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: