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Structure of 39989-43-0
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3,5-Dichlorobenzylamine features a benzylamine scaffold substituted with chlorine atoms at the 3 and 5 positions, delivering enhanced electron-withdrawing character and improved metabolic stability. This configuration supports efficient coupling in amide bond formation and facilitates incorporation into bioactive scaffolds requiring halogenated aromatic moieties.
3,5-Dichlorobenzylamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-dichloro substitution enhances metabolic stability and modulates lipophilicity, while the primary amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for scale-up and routine synthetic workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: