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Structure of 40117-63-3
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1-Azabicyclo[2.2.2]octane-4-carboxylic acid hydrochloride delivers a rigid, electron-deficient scaffold ideal for medicinal chemistry applications. This bench-stable derivative integrates seamlessly into bioactive molecule design, offering enhanced metabolic stability and predictable conformational behavior in target engagement studies.
1-Azabicyclo[2.2.2]octane-4-carboxylic acid hydrochloride serves as a rigid, conformationally constrained scaffold for medicinal chemistry applications. Its bicyclic structure imparts enhanced metabolic stability and defined spatial orientation, facilitating precise ligand-receptor interactions. The carboxylic acid functionality enables direct derivatization or salt formation, while the hydrochloride salt ensures improved solubility and handling stability in aqueous media. This compound functions effectively in peptide mimetics, kinase inhibitors, and CNS-targeted molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: