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Structure of 401567-00-8
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2-Chloro-1H-benzo[d]imidazole-5-carbonitrile features a rigid heterocyclic core with complementary electron-withdrawing groups: a chloro substituent at the 2-position and a nitrile group at the 5-position. This combination enhances electrophilicity at the imidazole ring, enabling efficient coupling reactions in medicinal chemistry. The molecule exhibits bench-stable handling characteristics and good solubility in common organic solvents, facilitating use in synthesis workflows.
2-Chloro-1H-benzo[d]imidazole-5-carbonitrile serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of biologically relevant scaffolds. Its ortho-chloro and nitrile groups facilitate palladium-catalyzed cross-coupling reactions and nucleophilic substitution processes under mild conditions. The compound exhibits excellent bench stability and compatibility with common protecting group strategies, supporting its use in multi-step syntheses and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: