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Structure of 403854-21-7
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4,5-Dichloropyrimidin-2-amine features a dual chloro substitution at the 4- and 5-positions of the pyrimidine ring, imparting enhanced electrophilicity and reactivity. This electron-deficient scaffold integrates readily into heterocyclic architectures, serving as a pivotal building block in medicinal chemistry and agrochemical synthesis. The amine functionality enables straightforward derivatization via coupling reactions.
4,5-Dichloropyrimidin-2-amine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds. Its dual chloro substituents at C4 and C5 facilitate nucleophilic substitution reactions with amines, thiols, and other soft nucleophiles, allowing rapid diversification. The molecule exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis campaigns and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: