5-Chloro-4-methylpyrimidin-2-amine

Name: 5-Chloro-4-methylpyrimidin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 40439-76-7
Cat. No. CS-0045818
Purity≥97%
MDL No.MFCD16877745

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloro-4-methylpyrimidin-2-amine|CS-0045818

Structure of 40439-76-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Chloro-4-methylpyrimidin-2-amine serves as a key heterocyclic scaffold in medicinal chemistry, featuring a chlorinated pyrimidine core with a methyl group at C4 and an amino function at C2. This combination delivers enhanced metabolic stability and favorable electronic properties, enabling efficient coupling in cross-coupling reactions and facilitating the synthesis of kinase inhibitors and antiviral agents.

Application

5-Chloro-4-methylpyrimidin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its ortho-chloro and amino groups facilitate palladium-catalyzed cross-coupling reactions and nucleophilic substitution, while the methyl group enhances metabolic stability. The compound exhibits excellent bench stability and ease of purification, making it well-suited for scalable synthesis and API development workflows.

General Information

CAS No. 40439-76-7
Cat. No. CS-0045818
Purity ≥97%
MDL No. MFCD16877745
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₆ClN₃
Molecular Weight 143.57
Synonym(s) 5-Chloro-4-methyl-pyrimidin-2-ylamine
SMILES NC1=NC=C(Cl)C(C)=N1

Computational Chemistry Data

TPSA 51.8
LogP 1.02062
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

5-Chloro-4-methylpyrimidin-2-amine sigma5-Chloro-4-methylpyrimidin-2-amine manufacturer5-Chloro-4-methylpyrimidin-2-amine price5-Chloro-4-methylpyrimidin-2-amine structure5-Chloro-4-methylpyrimidin-2-amine SDSbuy 5-Chloro-4-methylpyrimidin-2-amine5-Chloro-4-methylpyrimidin-2-amine supplier5-Chloro-4-methylpyrimidin-2-amine uses5-Chloro-4-methylpyrimidin-2-amine molecular weightprice of 5-Chloro-4-methylpyrimidin-2-amine5-Chloro-4-methylpyrimidin-2-amine chemical name formula of 5-Chloro-4-methylpyrimidin-2-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Chloro-4-methylpyrimidin-2-amine

CAS No. 40439-76-7

Recommended Products