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Structure of 405939-79-9
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4-Iodopicolinic acid is a bench-stable, moisture-tolerant heterocyclic carboxylic acid featuring a para-iodinated pyridine ring. This iodine moiety enables direct coupling in cross-coupling reactions, while the carboxylic acid group provides a versatile anchor for peptide synthesis and conjugation workflows under standard conditions.
4-Iodopicolinic acid serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling direct functionalization at the pyridine ring via cross-coupling reactions. Its iodine substituent facilitates palladium-catalyzed transformations, while the carboxylic acid group allows for derivatization through amide formation, esterification, or activation for coupling. The molecule exhibits excellent bench stability and compatibility with diverse reaction conditions, making it a reliable scaffold for constructing bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: