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CS-W001157 4
Total: USD 88.00

3,4-Dichloro-N-methylaniline

  • CAS No. 40750-59-2

  • Cat. No. CS-0139212
  • Purity≥98%
  • MDL No.MFCD00052850
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3,4-Dichloro-N-methylaniline|CS-0139212

Structure of 40750-59-2

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Description

3,4-Dichloro-N-methylaniline features a dual chlorination pattern that enhances electron-withdrawing character, enabling selective coupling reactions. The N-methyl group improves solubility and reduces basicity compared to the parent aniline, offering enhanced stability under standard bench conditions. This derivative serves as a key intermediate in pharmaceutical synthesis and functional material development.

Application

3,4-Dichloro-N-methylaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced electron-withdrawing character from the dichloro substitution. Its N-methylated amine functionality enables direct use in Suzuki-Miyaura couplings and reductive amination protocols, while maintaining bench stability and ease of purification. The compound functions as a versatile intermediate for constructing substituted aromatic scaffolds with defined electronic profiles.

General Information

  • CAS No. 40750-59-2
  • Cat. No. CS-0139212
  • Purity ≥98%
  • MDL No. MFCD00052850
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇Cl₂N
  • Molecular Weight 176.04
  • Synonym(s) N-Methyl-3,4-dichloroaniline
  • SMILES CNC1=CC=C(Cl)C(Cl)=C1

Computational Chemistry Data

  • TPSA   12.03
  • LogP   3.0351
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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