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CS-W001157 4
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tert-Butyl (chloromethyl) succinate

  • CAS No. 432037-43-9

  • Cat. No. CS-0197232
  • Purity≥96%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (chloromethyl) succinate|CS-0197232

Structure of 432037-43-9

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Description

tert-Butyl (chloromethyl) succinate features a reactive chloromethyl group flanked by a succinate ester and sterically hindered tert-butyl moiety, enabling selective alkylation under mild conditions. This combination delivers robust stability during handling while facilitating efficient conjugation in synthetic workflows.

Application

tert-Butyl (chloromethyl) succinate serves as a versatile bifunctional synthon, enabling efficient installation of both ester and chloromethyl handles in one molecule. The chloromethyl group facilitates alkylation reactions under mild conditions, while the tert-butyl ester provides orthogonal protection compatible with standard deprotection protocols. Its bench-stable nature and ease of purification make it ideal for multi-step synthesis of complex scaffolds, including heterocyclic systems and peptide analogs.

General Information

  • CAS No. 432037-43-9
  • Cat. No. CS-0197232
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅ClO₄
  • Molecular Weight 222.67
  • Synonym(s) Tert-Butyl Chloromethylsuccinate
  • SMILES CC(C)(C)OC(=O)CCC(=O)OCCl

Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.8478
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group :
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501

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