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CS-W001157 4
Total: USD 88.00

5-Chlorobenzo[d]isothiazol-3-ol

  • CAS No. 4337-43-3

  • Cat. No. CS-0270661
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Chlorobenzo[d]isothiazol-3-ol|CS-0270661

Structure of 4337-43-3

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General Information

  • CAS No. 4337-43-3
  • Cat. No. CS-0270661
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClNOS
  • Molecular Weight 185.63
  • Synonym(s) 5-Chloro-1,2-benzisothiazolin-3-one
  • SMILES C1=CC2=C(C=C1Cl)C(=NS2)O

Description

5-Chlorobenzo[d]isothiazol-3-ol features a chlorinated benzene ring fused to an isothiazolone scaffold, delivering enhanced stability and potent biocidal activity. This bench-stable compound integrates readily into antimicrobial formulations and serves as a key intermediate in the synthesis of functionalized heterocycles.

Synthesis

  • Route1
    • null|null
      256947-58-7
    • ~76%
    • In-stock
      5-Chlorobenzo[d]isothiazol-3-ol|CS-0270661
      4337-43-3

    References

    • Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012
  • Route2
    • null|null
      19993-65-8
    • ~%
    • In-stock
      5-Chlorobenzo[d]isothiazol-3-ol|CS-0270661
      4337-43-3

    References

    • Miura, Yozo Journal of Organic Chemistry, 1988 , vol. 53, # 12 p. 2850 - 2852
  • Route3
    • Methyl 5-chloro-2-mercaptobenzoate|CS-0634233
      52948-10-4
    • ~%
    • In-stock
      5-Chlorobenzo[d]isothiazol-3-ol|CS-0270661
      4337-43-3

    References

    • Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.6553
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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