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Structure of 438056-69-0
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4-(4-Aminophenyl)morpholin-3-one features a conjugated aniline linkage fused to a morpholinone core, delivering enhanced solubility and stability under standard bench conditions. This scaffold integrates readily into pharmaceutical intermediates, where the electron-rich aryl amine enables efficient coupling reactions. The ketone functionality serves as a key handle for derivatization in medicinal chemistry campaigns.
4-(4-Aminophenyl)morpholin-3-one serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. Its aniline moiety offers direct access to arylated scaffolds common in kinase inhibitors and CNS-targeted therapeutics. The morpholinone core provides enhanced solubility and metabolic stability, while the amine group facilitates further derivatization via acylation, alkylation, or cross-coupling. Bench-stable and readily purified by crystallization, it functions efficiently in multi-step syntheses under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: