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CS-W001157 4
Total: USD 88.00

2-Aminopurine

  • CAS No. 452-06-2

  • Cat. No. CS-W013358
  • Molecule weight135.13
  • Purity≥98%
  • MDL No.MFCD00005566

*For research and further manufacturing use only, not for direct human use.

2-Aminopurine|CS-W013358

Structure of 452-06-2

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General Information

  • CAS No. 452-06-2
  • Cat. No. CS-W013358
  • Purity ≥98%
  • MDL No. MFCD00005566
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅N₅
  • Molecular Weight 135.13
  • Synonym(s) None
  • SMILES NC1=NC=C2NC=NC2=N1

Description

Inhibiting double-stranded RNA-dependent protein kinase (PKR) activation, 2-Aminopurine (CAS 452-06-2) suppresses phosphorylation of eIF2α and blocks stress-induced translational arrest in mammalian cell models.

Application

2-Aminopurine (CAS 452-06-2) serves as a certified reference material enabling precise calibration in pharmaceutical release testing and method development for quantitative and qualitative analysis. It ensures traceability across labs. This standard supports rigorous quality control in food and beverage sectors, validating analytical workflows with confidence.

Synthesis

  • Route1
    • 2-Amino-6-chloropurine Clofarabine Impurity|CS-0229147
      10310-21-1
    • ~85%
    • In-stock
      2-Aminopurine|CS-W013358
      452-06-2

    References

    • Kusmierek, Jaroslaw; Czochralska, Barbara; Johansson, Nils Gunnar; Shugar, David Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 10 p. 701 - 707
  • Route2
    • null|null
      61991-08-0
    • ~48%
    • In-stock
      2-Aminopurine|CS-W013358
      452-06-2

    References

    • Goto; Toya; Ohgi; Kondo Tetrahedron Letters, 1982 , vol. 23, # 12 p. 1271 - 1274
  • Route3
    • null|null
      33512-51-5
    • ~90%
    • In-stock
      2-Aminopurine|CS-W013358
      452-06-2

    References

    • Kos, Nico J.; Plas, Henk C. van der Journal of Organic Chemistry, 1980 , vol. 45, # 15 p. 2942 - 2945

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.48
  • LogP   -0.0649
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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