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Structure of 455-25-4
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4-Acetylbenzene-1-sulfonyl fluoride is a reactive acylating agent featuring a sulfonyl fluoride group flanked by an electron-withdrawing acetyl substituent. This combination enhances electrophilicity at the sulfonyl center, enabling efficient coupling with nucleophiles in mild conditions. The molecule exhibits bench-stable handling characteristics and delivers high functional group tolerance, making it well-suited for selective protein labeling and bioconjugation workflows.
4-Acetylbenzene-1-sulfonyl fluoride serves as a versatile electrophilic sulfonylating agent, enabling efficient introduction of sulfonate groups under mild conditions. Its acetyl functionality provides orthogonal reactivity for subsequent transformations, while the sulfonyl fluoride moiety offers high stability and compatibility with diverse functional groups. Ideal for late-stage functionalization in medicinal chemistry, it facilitates rapid access to sulfonamide-containing scaffolds with excellent bench stability and straightforward purification.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H315
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: