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Structure of 458543-81-2
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Ethyl 3-amino-2,6-dichloroisonicotinate features a sterically hindered isonicotinate core with electron-deficient chlorine substituents at the 2- and 6-positions. The pendant amino group enables direct functionalization in late-stage synthesis, while the ethyl ester facilitates efficient derivatization. This compound delivers a robust platform for constructing bioactive heterocycles under standard conditions.
Ethyl 3-amino-2,6-dichloroisonicotinate serves as a versatile building block in the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-dichloro substitution enables selective functionalization, while the pendant amino and ester groups offer complementary reactivity for coupling, amidation, and cyclization reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable medicinal chemistry campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: