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Structure of 461-97-2
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3,5-Dimethylfluorobenzene features a fluorine atom flanked by two methyl groups at the 3- and 5-positions, creating a sterically hindered, electron-rich aromatic core. This configuration enhances stability and facilitates selective electrophilic substitution. The compound serves as a valuable scaffold in medicinal chemistry and agrochemical synthesis, offering predictable reactivity and improved metabolic resistance.
3,5-Dimethylfluorobenzene serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced metabolic stability and lipophilicity due to its ortho-alkylated aryl fluoride motif. The molecule exhibits excellent bench stability, facilitates efficient Suzuki-Miyaura coupling reactions, and functions as a versatile scaffold for constructing complex heterocyclic systems through standard electrophilic substitution or transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: