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Structure of 462-40-8
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1-Fluoro-3-iodopropane is a bifunctional alkylating agent featuring a fluorine atom and an iodine group at terminal positions of a three-carbon chain. This arrangement enables sequential functionalization in cross-coupling and nucleophilic substitution reactions. The molecule exhibits high reactivity toward soft nucleophiles, facilitating efficient C–C and C–heteroatom bond formation under mild conditions. Its stability under standard handling protocols supports reliable use in synthetic workflows.
1-Fluoro-3-iodopropane serves as a versatile bifunctional building block for C–C and C–heteroatom bond formation. The fluorine and iodine termini enable sequential cross-coupling reactions, including Suzuki-Miyaura and Negishi couplings, with high chemoselectivity. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate efficient synthesis of linear alkyl chains and heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: