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CS-W001157 4
Total: USD 88.00

6-Methoxy-5-nitropicolinic acid

  • CAS No. 475272-62-9

  • Cat. No. CS-0040710
  • Purity≥97%
  • MDL No.MFCD18261308
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-5-nitropicolinic acid|CS-0040710

Structure of 475272-62-9

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Description

6-Methoxy-5-nitropicolinic acid features a pyridine core functionalized with a nitro group at C5 and a methoxy substituent at C6, delivering enhanced electron-withdrawing character and improved solubility. This combination enables efficient coordination in metal-ligand systems and facilitates downstream derivatization in synthetic applications requiring polar, bench-stable intermediates.

Application

6-Methoxy-5-nitropicolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through its orthogonal functionalization potential. The nitro group facilitates reduction and subsequent coupling reactions, while the methoxy substituent enhances solubility and modulates electronic properties. This compound exhibits bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis workflows and API scaffold development.

General Information

  • CAS No. 475272-62-9
  • Cat. No. CS-0040710
  • Purity ≥97%
  • MDL No. MFCD18261308
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O₅
  • Molecular Weight 198.13
  • Synonym(s) 6-Methoxy-5-nitro-pyridine-2-carboxylic acid
  • SMILES O=C(C1=NC(OC)=C([N+]([O-])=O)C=C1)O

Computational Chemistry Data

  • TPSA   102.56
  • LogP   0.6966
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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