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Structure of 475272-62-9
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6-Methoxy-5-nitropicolinic acid features a pyridine core functionalized with a nitro group at C5 and a methoxy substituent at C6, delivering enhanced electron-withdrawing character and improved solubility. This combination enables efficient coordination in metal-ligand systems and facilitates downstream derivatization in synthetic applications requiring polar, bench-stable intermediates.
6-Methoxy-5-nitropicolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through its orthogonal functionalization potential. The nitro group facilitates reduction and subsequent coupling reactions, while the methoxy substituent enhances solubility and modulates electronic properties. This compound exhibits bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis workflows and API scaffold development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: