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Structure of 479028-72-3
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Imidazo[1,2-a]pyridine-5-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 5-position, enabling direct integration into bioactive molecules. The scaffold exhibits enhanced metabolic stability and favorable solubility profiles under physiological conditions. This compound serves as a key structural motif in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active agents.
Imidazo[1,2-a]pyridine-5-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization. Its carboxylic acid group facilitates direct derivatization via amide coupling or esterification, while the fused imidazopyridine core exhibits favorable metabolic stability and moderate lipophilicity. The compound demonstrates bench stability and compatibility with common purification methods, making it well-suited for high-throughput synthesis and structure–activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: