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CS-W001157 4
Total: USD 88.00

Boc-NH-ethyl-SS-propionic acid

  • CAS No. 485800-27-9

  • Cat. No. CS-0115530
  • Purity≥95%
  • MDL No.MFCD19443373

*For research and further manufacturing use only, not for direct human use.

Boc-NH-ethyl-SS-propionic acid|CS-0115530

Structure of 485800-27-9

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General Information

  • CAS No. 485800-27-9
  • Cat. No. CS-0115530
  • Purity ≥95%
  • MDL No. MFCD19443373
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₄S₂
  • Molecular Weight 281.39
  • Synonym(s) None
  • SMILES O=C(O)CCSSCCNC(OC(C)(C)C)=O

Description

Boc-NH-ethyl-SS-propionic acid is a sulfide-linked amino acid derivative featuring a tert-butoxycarbonyl-protected amine and a disulfide bridge. This bifunctional reagent enables site-specific conjugation in bioconjugation workflows, offering stable linkage under physiological conditions. The disulfide bond cleaves selectively in reducing environments, facilitating controlled release in targeted delivery systems.

Application

Boc-NH-ethyl-SS-propionic acid serves as a versatile sulfide-containing building block for the synthesis of thioether-functionalized peptides and bioactive molecules. Its stability under standard coupling conditions, combined with orthogonal Boc deprotection and facile sulfur oxidation potential, enables reliable access to diverse sulfanyl scaffolds in medicinal chemistry and peptide macrocyclization workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.3672
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   7

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