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Structure of 49713-58-8
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4-Chloroquinoline-7-carboxylic acid features a chlorine-substituted quinoline core with a carboxylic acid group at the C7 position, enabling direct conjugation in synthetic transformations. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and serves as a key building block for bioactive molecule development under standard conditions.
4-Chloroquinoline-7-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C7 position via palladium-catalyzed cross-coupling reactions. Its stability under standard synthetic conditions and compatibility with diverse nucleophiles facilitate efficient access to quinoline-based pharmacophores. The carboxylic acid group supports derivatization through amide bond formation or esterification, enhancing solubility and bioavailability profiles. This compound functions as a key scaffold for developing kinase inhibitors and other targeted therapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: