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CS-W001157 4
Total: USD 88.00

(3-Chloropyridin-2-yl)methanamine

  • CAS No. 500305-98-6

  • Cat. No. CS-W007044
  • Purity≥98%
  • MDL No.MFCD05664032

*For research and further manufacturing use only, not for direct human use.

(3-Chloropyridin-2-yl)methanamine|CS-W007044

Structure of 500305-98-6

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General Information

  • CAS No. 500305-98-6
  • Cat. No. CS-W007044
  • Purity ≥98%
  • MDL No. MFCD05664032
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇ClN₂
  • Molecular Weight 142.59
  • Synonym(s) 2-Pyridinemethanamine,3-chloro-(9CI)
  • SMILES NCC1=NC=CC=C1Cl

Description

(3-Chloropyridin-2-yl)methanamine features a chlorinated pyridine core with a primary amine tethered to the 3-position, enabling direct functionalization in heterocyclic synthesis. This bench-stable, moisture-tolerant building block integrates readily into pharmaceutical intermediates and ligand frameworks through nucleophilic substitution or coupling reactions.

Application

(3-Chloropyridin-2-yl)methanamine serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the pyridine nitrogen and ortho-position. Its amine functionality facilitates coupling reactions, while the chlorine atom provides a site for palladium-catalyzed cross-coupling or nucleophilic substitution. The compound exhibits bench stability and compatibility with common protecting group strategies, making it well-suited for medicinal chemistry campaigns requiring modular scaffold assembly.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.1937
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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