Fmoc-(S)-3-Amino-3-(3-pyridyl)-propionic acid

Name: Fmoc-(S)-3-Amino-3-(3-pyridyl)-propionic acid
Brand: ChemScene
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CAS No. 507472-06-2
Cat. No. CS-0179098
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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Fmoc-(S)-3-Amino-3-(3-pyridyl)-propionic acid|CS-0179098

Structure of 507472-06-2

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General Information

CAS No. 507472-06-2
Cat. No. CS-0179098
Purity ≥95%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₀N₂O₄
Molecular Weight 388.42
Synonym(s) (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyridin-3-yl)propanoic acid
SMILES O=C(O)C[C@@H](C1=CN=CC=C1)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O

Description

Fmoc-(S)-3-Amino-3-(3-pyridyl)-propionic acid is a specialized amino acid derivative designed for solid-phase peptide synthesis. The Fmoc group enables efficient N-terminal protection, while the 3-pyridyl moiety imparts enhanced solubility and facilitates downstream functionalization. This residue integrates readily into peptide sequences under standard coupling conditions, offering robust stability and compatibility with common deprotection protocols.

Application

Fmoc-(S)-3-Amino-3-(3-pyridyl)-propionic acid serves as a versatile building block for the synthesis of peptide conjugates and bioactive scaffolds. The Fmoc group enables efficient solid-phase peptide synthesis, while the 3-pyridyl moiety provides a polar, heteroaromatic handle amenable to metal-catalyzed coupling and functionalization. Its stability under standard deprotection conditions and compatibility with common protecting groups facilitate straightforward purification and incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

TPSA 88.52
LogP 4.1361
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 6

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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Fmoc-(S)-3-Amino-3-(3-pyridyl)-propionic acid

CAS No. 507472-06-2

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