Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)pr opionic acid

Name: Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)pr opionic acid
Brand: ChemScene
Availability: InStock
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CAS No. 511272-32-5
Cat. No. CS-0179102
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)pr opionic acid|CS-0179102

Structure of 511272-32-5

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Description

Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)propionic acid is a chiral amino acid derivative featuring a methoxy-substituted phenyl group and a stable Fmoc protecting group. This scaffold enables efficient incorporation into peptide chains under standard coupling conditions, offering enhanced solubility and reduced aggregation during synthesis.

Application

Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)propionic acid serves as a valuable building block for the synthesis of peptide conjugates and bioactive scaffolds. The Fmoc group enables efficient solid-phase peptide synthesis, while the pendant 3-methoxyphenyl moiety offers enhanced solubility and potential for downstream functionalization. Its stability under standard coupling conditions and compatibility with diverse reaction environments make it a practical choice for medicinal chemistry campaigns requiring aromatic side-chain diversity.

General Information

CAS No. 511272-32-5
Cat. No. CS-0179102
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₅H₂₃NO₅
Molecular Weight 417.45
Synonym(s) FMOC-(R)-3-AMINO-3-(3-METHOXY-PHENYL)-PROPIONIC ACID
SMILES COC1=CC=CC([C@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)CC(O)=O)=C1

Computational Chemistry Data

TPSA 84.86
LogP 4.7497
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 7

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Ester

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)pr opionic acid

CAS No. 511272-32-5

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