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Structure of 51454-63-8
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2-(Hydroxymethyl)isonicotinonitrile features a pyridine ring bearing both nitrile and hydroxymethyl functional groups in the meta orientation, enabling dual reactivity. This bench-stable derivative integrates readily into synthetic sequences requiring polar, electron-deficient heterocycles with tailored handle sites for downstream conjugation or transformation.
2-(Hydroxymethyl)isonicotinonitrile serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds through established transformations. Its nitrile and hydroxymethyl functionalities offer orthogonal reactivity, facilitating selective derivatization under mild conditions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: