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Structure of 52107-46-7
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4-Chlorothiazol-2-amine features a thiazole core with strategically positioned chlorine and amino groups, enabling direct functionalization in heterocyclic synthesis. The electron-deficient ring facilitates nucleophilic substitution, while the amine moiety serves as a reactive handle for coupling reactions. This compound offers enhanced stability under standard conditions and demonstrates compatibility with diverse reaction environments.
4-Chlorothiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct functionalization at the 2-position via nucleophilic substitution or palladium-catalyzed coupling. Its chlorine substituent provides high reactivity for C–N and C–C bond formation, while the amino group offers orthogonal handle for derivatization. Bench-stable and readily purified by recrystallization, it facilitates efficient access to thiazole-based scaffolds prevalent in pharmaceutical research.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: