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Structure of 52205-85-3
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This sulfonyl chloride derivative features a rigid, aromatic-indene scaffold that enhances reactivity and stability. The 5-sulfonyl chloride group enables efficient coupling reactions in synthetic routes to functionalized heterocycles and bioactive molecules. Bench-stable under standard conditions, it integrates seamlessly into pharmaceutical intermediates and materials chemistry workflows.
2,3-Dihydro-1H-indene-5-sulfonyl chloride serves as a versatile sulfonyl chloride building block for the synthesis of sulfonamide-containing compounds. Its reactive sulfonyl chloride group enables efficient coupling with amines under mild conditions, facilitating access to pharmaceutically relevant scaffolds. The rigid, hydrophobic indene core provides structural diversity and enhanced metabolic stability, making it valuable in medicinal chemistry campaigns targeting kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: