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Structure of 52548-14-8
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5-Methyl-2-iodobenzoic acid features a strategically positioned iodine atom and methyl group on the aromatic ring, enabling direct functionalization in cross-coupling reactions. This bench-stable derivative integrates readily into synthetic sequences requiring halogen-directed derivatization, offering predictable reactivity under standard conditions.
5-Methyl-2-iodobenzoic acid serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The iodide group exhibits high reactivity with minimal side processes, while the carboxylic acid functionality allows for direct derivatization or use in amide coupling protocols. Bench-stable and compatible with diverse functional groups, it facilitates streamlined synthesis of substituted aromatic scaffolds relevant to medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: