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Structure of 52583-87-6
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2-(Methylamino)nicotinonitrile features a pyridine core bearing a methylamino group at the 2-position and a nitrile at the 3-position, delivering enhanced solubility and reactivity in synthetic transformations. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates, particularly in kinase inhibitor scaffolds, under standard conditions. The nitrile moiety enables downstream functionalization via nucleophilic addition or reduction.
2-(Methylamino)nicotinonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through its dual functionality: the nitrile group facilitates nucleophilic additions and cyclizations, while the methylamino moiety supports facile derivatization. Its bench-stable nature and compatibility with standard coupling and protection protocols make it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: