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Structure of 5266-85-3
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2-Isopropyl-6-methylaniline delivers a sterically hindered aryl amine scaffold with enhanced solubility and thermal stability. This ortho-substituted aniline features a para-directing methyl group and an isopropyl moiety that imparts electronic modulation, enabling efficient coupling in cross-coupling reactions and facilitating incorporation into functionalized aromatic systems under standard conditions.
2-Isopropyl-6-methylaniline serves as a valuable aryl amine building block in medicinal chemistry and agrochemical synthesis, offering enhanced lipophilicity and steric bulk compared to simpler anilines. Its ortho-substituted structure provides improved metabolic stability and facilitates selective functionalization in late-stage derivatization. The compound exhibits excellent bench stability and is compatible with standard coupling reactions, enabling efficient access to diverse heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H302-H315-H319
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P302+P352-P330-P362+P364-P370+P378-P501
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Lot numbers can be found on the outside label of a product: