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CS-W001157 4
Total: USD 88.00

2-Isopropyl-6-methylaniline

  • CAS No. 5266-85-3

  • Cat. No. CS-W020539
  • Purity≥96%
  • MDL No.MFCD00007746
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Isopropyl-6-methylaniline|CS-W020539

Structure of 5266-85-3

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Description

2-Isopropyl-6-methylaniline delivers a sterically hindered aryl amine scaffold with enhanced solubility and thermal stability. This ortho-substituted aniline features a para-directing methyl group and an isopropyl moiety that imparts electronic modulation, enabling efficient coupling in cross-coupling reactions and facilitating incorporation into functionalized aromatic systems under standard conditions.

Application

2-Isopropyl-6-methylaniline serves as a valuable aryl amine building block in medicinal chemistry and agrochemical synthesis, offering enhanced lipophilicity and steric bulk compared to simpler anilines. Its ortho-substituted structure provides improved metabolic stability and facilitates selective functionalization in late-stage derivatization. The compound exhibits excellent bench stability and is compatible with standard coupling reactions, enabling efficient access to diverse heterocyclic scaffolds and API intermediates.

General Information

  • CAS No. 5266-85-3
  • Cat. No. CS-W020539
  • Purity ≥96%
  • MDL No. MFCD00007746
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅N
  • Molecular Weight 149.23
  • Synonym(s) 6-Isopropyl-o-toluidine
  • SMILES NC1=C(C(C)C)C=CC=C1C

Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.70062
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225-H302-H315-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P302+P352-P330-P362+P364-P370+P378-P501

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