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CS-W001157 4
Total: USD 88.00

4-(((Benzyloxy)carbonyl)amino)benzoic acid

  • CAS No. 5330-71-2

  • Cat. No. CS-0453337
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(((Benzyloxy)carbonyl)amino)benzoic acid|CS-0453337

Structure of 5330-71-2

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Description

4-(((Benzyloxy)carbonyl)amino)benzoic acid features a benzyl-protected amino group flanked by a para-carboxylic acid, enabling selective deprotection in peptide synthesis. This dual-functional scaffold integrates seamlessly into orthogonal protection strategies, offering stable handling and precise coupling control under standard conditions.

Application

4-(((Benzyloxy)carbonyl)amino)benzoic acid serves as a versatile protected amino acid building block, enabling efficient peptide synthesis through orthogonal protection of both amine and carboxylic acid functionalities. The benzyloxycarbonyl (Z) group offers excellent stability under standard reaction conditions and can be selectively removed via hydrogenolysis, facilitating downstream functionalization. Its compatibility with diverse coupling protocols and ease of purification make it a practical choice for multi-step synthetic sequences in medicinal chemistry and API development.

General Information

  • CAS No. 5330-71-2
  • Cat. No. CS-0453337
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₃NO₄
  • Molecular Weight 271.27
  • Synonym(s) Benzoic acid, 4-[[(phenylmethoxy)carbonyl]amino]- (9CI)
  • SMILES C1=CC=C(C=C1)COC(=O)NC2=CC=C(C=C2)C(=O)O

Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.1335
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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