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Structure of 53574-58-6
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5-Formylpicolinic acid delivers a reactive aldehyde group at the 5-position of a picolinic acid scaffold, enabling direct conjugation in bioconjugation and probe development. This electron-deficient heterocycle features enhanced solubility and stability under standard conditions, facilitating efficient coupling with nucleophiles such as hydrazides and amines.
5-Formylpicolinic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds via condensation and cyclization reactions. Its ortho-aldehyde and carboxylic acid functionalities offer complementary reactivity for diversification, including amide formation, imine assembly, and transition-metal-catalyzed couplings. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: