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Structure of 54136-24-2
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5-Bromo-2,3,3-trimethyl-3H-indole is a sterically hindered indole derivative featuring a bromine substituent at the 5-position and three methyl groups concentrated at the 3-position. This configuration imparts enhanced stability and resistance to decomposition under standard bench conditions. The molecule serves as a valuable scaffold for constructing complex heterocyclic systems in medicinal chemistry and materials science applications.
5-Bromo-2,3,3-trimethyl-3H-indole serves as a versatile building block for brominated indole scaffolds in medicinal chemistry and materials science. Its stability under standard reaction conditions enables direct use in Pd-catalyzed cross-couplings, facilitating the synthesis of complex biaryl systems. The trimethyl substitution enhances solubility and reduces aggregation, while the bromine at C5 provides a reliable site for functionalization. This compound functions effectively in late-stage diversification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: