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Structure of 773-63-7
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2,3,3-Trimethyl-3H-indol-5-amine features a sterically hindered indole core with a primary amine at the 5-position, enabling direct functionalization in synthetic transformations. The methyl groups enhance stability and solubility in organic media, while the electron-rich indole scaffold facilitates coupling reactions under mild conditions. This derivative serves as a robust building block for bioactive heterocycles and fluorescent probes.
2,3,3-Trimethyl-3H-indol-5-amine serves as a versatile building block for indole-based scaffolds in medicinal chemistry. Its electron-rich aromatic core and pendant primary amine facilitate downstream functionalization via amidation, alkylation, or transition-metal-catalyzed coupling. The trimethyl substitution enhances solubility and metabolic stability, while the 3H-indol structure ensures compatibility with standard heterocycle synthesis protocols. Ideal for rapid library generation and lead optimization in CNS-targeted drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: