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CS-W001157 4
Total: USD 88.00

4-Phenylcyclohexanol

  • CAS No. 5437-46-7

  • Cat. No. CS-0187050
  • Molecule weight176.25
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Phenylcyclohexanol|CS-0187050

Structure of 5437-46-7

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General Information

  • CAS No. 5437-46-7
  • Cat. No. CS-0187050
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆O
  • Molecular Weight 176.25
  • Synonym(s) NSC 17139
  • SMILES C1=CC=C(C=C1)C2CCC(CC2)O

Description

4-Phenylcyclohexanol features a rigid cyclohexanol core functionalized with a pendant phenyl ring, delivering enhanced structural stability and tunable lipophilicity. This scaffold integrates readily into chiral auxiliaries and serves as a key intermediate in asymmetric synthesis. The hydroxyl group enables direct derivatization, while the aromatic moiety supports π–π interactions in molecular recognition systems.

Application

4-Phenylcyclohexanol serves as a versatile chiral building block in synthetic organic chemistry, enabling the construction of complex cyclohexane-based scaffolds. Its stable tertiary alcohol functionality and aryl substituent facilitate downstream transformations such as dehydrogenation, oxidation, and coupling reactions. The molecule exhibits favorable bench stability and ease of purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.7051
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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