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CS-W001157 4
Total: USD 88.00

cis-3-Hydroxycyclobutanecarboxylic acid

  • CAS No. 552849-33-9

  • Cat. No. CS-W005391
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD12964956

*For research and further manufacturing use only, not for direct human use.

cis-3-Hydroxycyclobutanecarboxylic acid|CS-W005391

Structure of 552849-33-9

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General Information

  • CAS No. 552849-33-9
  • Cat. No. CS-W005391
  • Purity ≥97%
  • MDL No. MFCD12964956
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₃
  • Molecular Weight None
  • Synonym(s) cis-3-hydroxycyclobutanecarboxylicacid
  • SMILES O=C([C@H]1C[C@@H](O)C1)O

Description

cis-3-Hydroxycyclobutanecarboxylic acid features a rigid cyclobutane scaffold with adjacent hydroxyl and carboxylic acid groups in a cis configuration, enabling precise stereochemical control. This structural motif delivers enhanced polarity and hydrogen-bonding capacity, facilitating integration into bioactive molecules and chiral building blocks for medicinal chemistry applications.

Application

cis-3-Hydroxycyclobutanecarboxylic acid serves as a valuable chiral building block in synthetic organic chemistry, offering a rigid cyclobutane scaffold with orthogonal functional groups. Its cis configuration enables predictable stereochemical control in downstream transformations, while the hydroxyl and carboxylic acid moieties provide handles for derivatization, protection, or conjugation. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for applications in medicinal chemistry and natural product synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.1581
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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